Handbook of Herbal Formulation

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Herbal formulations play a significant role in maintaining health. The variety of novel herbal formulations like polymeric nanoparticles, nanocapsules, liposomes, phytosomes, nanoemulsions, microsphere, transferosomes, and ethosomes has been reported using bioactive and plant extracts. Novel herbal formulations have various advantages over the traditional formulations such as improved solubility and bioavailability, reduced toxicity, controlled drug delivery, protections of plant actives from degradation.

This book comprises many units - the first unit is well laid out and sequentially explores relevant topics like herbal formulation, definitions, classification, traditional vs modern herbal formulation and herbal dosage forms.

The details about formulation consideration of herbal dosage form, it provides number of examples of herbal excipient like colorants, flavouring agent with their evaluation guidelines. The chapter also contains comparison between herbal conventional formulation as well as herbal novel drug delivery.

Chapter 4 focuses on intellectually property rights and patenting of herbal formulations covering concepts of IPR, regulatory issues and documentation of patenting herbal formulations. The information presented in Chapters 5 and 6 primarily deal with nutraceuticals and cosmeceuticals herbal based formulation. Chapter 5 provides information on health benefits of nutraceuticals, regulatory requirements and worldwide scenario of nutraceuticals.

The next informative topics are evaluation of quality, efficacy and safety of herbal formulation, their quality consideration, efficacy assessment and safety concern of herbal formulation. The concise text containing status of herbal formulation related to trading, export and import, global market of herbal formulation. The relevant piece of information is herbal drugs commonly used for formulation developments including name of drug, active constituents and pharmacological efficacy.

In addition, book contains specific text on bioavailability of herbals, mechanism of action, ideal property of enhancer and herbs, source, mechanism and their dose as bioenhancers. The current need is pharmacovigilance of herbal medicines, challenges in monitoring safety of herbal medicines and WHO drug monitoring program.

Sapna Malviya MPharm (Hons), MBA (HR), PhD (Pharm Sci) is currently Professor and Head, Department of Pharmaceutical Sciences, Modern Institute of Pharmaceutical Sciences, Indore, MP. She has so far guided 30 graduate and 10 postgraduate level projects. She obtained her BPharm and MPharm degrees from BR Nahata College of Pharmacy, Mandsaur, and PhD from SGVU, Rajasthan. Major areas of her research interest include herbal drug standardization, ethnopharmacology and herbal formulation development. She has contributed 30 papers in national and international peer-reviewed journals, authored Textbook of Pharmacognover and Phytochemistry and Herbal Drug Technology, co-authored one book and contributed two chapters in the field of pharmaceutical sciences. She has coordinated various events of Indian Pharmaceutical Association (IPA) and Association of Pharmaceuticals Teachers of India (APTI).

Neelesh Malviya MPharm (Hons), MBA (HR), PhD (Pharm Sci) is currently Principal and Professor, Smriti College of Pharmaceutical Education, Indore, MP. He obtained his BPharm, MPharm and PhD degrees from BR Nahata College of Pharmacy, Mandsaur, MP. His areas of research include phytochemistry and herbal drug development. He has published more than 45 papers in various reputed peer-reviewed national and international journals. He has authored Textbook of Pharmacognosy and Phytochemistry and Herbal Drug Technology, co-authored two books, and contributed two chapters in the field of pharmaceutical sciences. He has guided 12 postgraduate and 20 graduate research projects to date, and is supervising 6 PhD and postgraduate research projects. He is an honorary life member of IPA, APTI and Society of Ethnopharmacology.

Handbook of Herbal Formulation is the result of abundant hard work of the authors. They have given entire details, right from what this actually means its impetus; the formulation development involved for applying herbs and its various benefits. The book highlighted on the herbs, its formulations and knowledge of traditional and modern pharmacognosy which can stand as a pillar for all postgraduate and undergraduate pharmacy students. The book provides entire details on various evolving topics of herbal formulation and highlighted its gravity.

In view of all-inclusive information of the subject, a textbook is engrossed to give determined pronounce of pharmacognosy. This modern version of herbal formulation emphasizes on definition, classification, herbal excipient, formulation development, conventional dosage form novel drug delivery, intellectual property rights and patenting of herbal formulations, nutraceuticals-herbal-based formulation, cosmeceuticals-herbal-based cosmetic preparation, evaluation of quality, efficacy and safety of herbal formulation, status of herbal formulation, bioavailability of herbals and pharmacovigilance of herbal medicine. The highlighted portion of the text focuses on general introduction to herbal formulation, presents scope and future prospects. In addition, it includes herbal drugs commonly used for formulation developments. The objective of the authors is fully achieved by systematic assemblage of the well-written chapters with neat and clean well-labelled diagram whenever necessary.

The authors convey deep sense of gratitude to their grandparents, parents and son to deeply motivating them to provide a kind of book required for undergraduate, postgraduate and researchers.

Doubtless authors are indebted to all who have supported in giving the present shape to the book.

Last but not least, the authors express heartfelt gratitude towards Mr YN Arjuna for his support, guidance and cooperation to publish this book Suggestions and criticism will always be solicited by the authors to further improve the quality of book in real sense.

The drugs from indigenous system of medicine, particularly herbal formulation modern drugs for preventive and curative purposes worldwide. The herbal formulations are considered to be safe as they consist of herbs or processed herbs to provide specific medicinal, nutritional or cosmetic benefits. The market is flooded with the products that are basically of herbal origin. In this paradigm shift the herbal formulations gained attention and witnessing an enormous escalation in demand in the national and international markets. Herbal products are substituting the synthetics products, as they are not having sharp biological activity and adverse effects. Herbal products are in gigantic demand in the developed world for healthcare as they are considered efficient, safe and have lesser side effects.

The present book is a sincere effort to address different issues associated with the formulation of modern dosage forms containing herbals. I believe that this book will be a connecting tool between traditional and modern dosage forms and would be useful to those who are working in this area. The handbook covers the area of intellectual property rights and patenting of herbal formulations, nutraceuticals, cosmeceuticals, bioavailability of herbals and pharmacovigilance of herbal medicine. The book will be useful to entrepreneurs, manufacturers of herbal products who can effortlessly extract the relevant formulation and process from the handbook.

I am sure this book will be useful to all stakeholders of pharmacy profession.

I congratulate the authors for this manuscript and wish all success for their endeavors.